SOCS2 polyclonal antibody
产品名称: SOCS2 polyclonal antibody
英文名称: SOCS2 polyclonal antibody
产品编号: PAB12779
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SOCS2.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human, mouse and rat SOCS2.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 23
- Reactivity:
- Bovine, Chicken, Dog, Human, Mouse, Rat
- Specificity:
- This antibody recognizes ~23 KDa of SOCS2.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (10% Proclin300)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Immunohistochemistry (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor.
Dey BR, Spence SL, Nissley P, Furlanetto RW.J Biol Chem. 1998 Sep 11;273(37):24095-101.
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Immunohistochemistry
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 8835
- Gene Name:
- SOCS2
- Gene Alias:
- CIS2,Cish2,SOCS-2,SSI-2,SSI2,STATI2
- Gene Description:
- suppressor of cytokine signaling 2
- Omim ID:
- 605117
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq
- Other Designations:
- STAT induced STAT inhibitor-2,cytokine-inducible SH2 protein 2,suppressor of cytokine signaling-2
- Entrez GeneID:
- 216233
- Gene Name:
- Socs2
- Gene Alias:
- 8030460M17,AI527257,AW108012,CIS2,Cish2,D130043N08Rik,JAB,MGC118106,SOCS-2,SSI-2,hg
- Gene Description:
- suppressor of cytokine signaling 2
- Gene Ontology:
- Hyperlink
- Other Designations:
- STAT-induced STAT inhibitor 2,cytokine inducible SH2-containing protein 2,cytokine-inducible SH2 protein 2